The D'Arcangelo Lab
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Yabut O., Domogauer J, D'Arcangelo G (2010) Dyrk1A overexpression inhibits proliferation and induces neuronal differentiation of neural progenitor cells. J Neurosci 30(11):4004-14.  | Pubmed

 
D'Arcangelo G (2009) From human tissue to animal models: insights into the   pathogenesis of cortical dysplasia.  Epilepsia 50 Suppl 9:28-33.  | Pubmed
 
Ljungberg MC, Sunnen CN, Lugo JN, Anderson AE, D'Arcangelo G (2009) Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia.  Dis Model Mech (7-8):389-98  | Pubmed
 
Zhang G, Assadi AH, Roceri M, Clark GD, D'Arcangelo G (2009) Differential interaction of the Pafah1b alpha subunits with the Reelin transducer Dab1.  Brain Res 1267:1-8.  | Pubmed
 
Niu S, Yabut O, D'Arcangelo G (2008) The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons.  J Neurosci 28(41):10339-48.  |  Pubmed
 
Pafah1b2 mutations suppress the development of the hydrocephalus in compound Pafah1b1; Reln and Pafah1b1; Dab1 mutant mice. Neurosci Lett. 439(1):100-5  |  Pubmed
 
Zhang G, Assadi AH, McNeil RS, Beffert U, Wynshaw-Boris A, Clark GD, D'Arcangelo G (2007)  The Pafah1b complex interacts with the reelin receptor VLDLR.  PLoS One 2(2):e252. |  Pubmed
 
Yabut O, Renfro A, Niu S, Swann JW, Marin O, D'Arcangelo G (2007)  Abnormal laminar position and dendrite development of interneurons in the reeler forebrain.  Brain Res 1140:75-83.  |  Pubmed
 
Ljungberg MC, Bhattacharjee MB, Lu Y, Armstrong DL, Yosher D, Swann JW, Sheldon M, D'Arcangelo G (2006)  Activation of mammalian target of rapamycin in cytomegalic neurons of human cortical dysplasia.  Ann Neurol  60(4):420-9.  |  Pubmed
 
D'Arcangelo G (2006) Reelin mouse mutants as models of cortical development disorders.  Epilepsy Behav 8(1):81-90.  |  Pubmed
 
D'Arcangelo G (2005)  The reeler mouse: anatomy of a mutant.  Int Rev Neurobiol  71:383-417.  |  Pubmed
 
D'Arcangelo G (2005)  Apoer2: a reelin receptor to remember.  Neuron  47(4):471-3  |  Pubmed
 
Niu A, Renfro A, Quattrocchi CC, Sheldon M, D'Arcangelo G (2004)  Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway.  Neuron  41(1):71-84.  |  Pubmed
 
Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D'Arcangelo G, Clark GD (2003) Interaction of reelin signaling and Lis1 in brain development.  Nat Genet 35(3):270-6.  |  Pubmed
 
Deguchi K, Inoue K, Avila WE, Lopez-Terrada D, Antaiffy BA, Quattrocchi CC, Sheldon M, Mikoshiba K, D'Arcangelo G, Armstrong DL (2003) Reelin and disabled-1 expression in developing and mature human cortical neurons.  J Neuropathol Exp Neurol 62(6):676-84.  |  Pubmed
 
Quattrocchi CC, Wannenes F, Persico AM, Ciafre SA, D'Arcangelo G, Farace MG, Keller F (2002)  Reelin is a serine protease of the extracellular matrix.  J Biol Chem 277(1):303-9  |  Pubmed
 
D'Arcangelo G (2001) The role of the Reelin pathway in cortical development.  Symp Soc Exp Biol 53:59-73.  | Pubmed
 
Bernier B, Bar I, D'Arcangelo G, Curran T, Goffinet AM (2000) Reelin mRNA expression during embryonic brain development in the chick.  J Comp Neurol  422(3):448-63.  |  Pubmed
 
D'Arcangelo G, Homayouni R, Keshvara L, Rice DS, Sheldon M, Curran T (1989)  Reelin is a ligand for lipoprotein receptors.  Neuron 24(2):471-9.  | Pubmed
 
Borrell V, Del Rio JA, Alcantara S, Derer M, Martinez A, D'Arcangelo G, Nakajima K, Mikoshiba K, Derer P, Curran T, Soriano E (1999)  Reelin regulates the development and synaptogenesis of the layer-specific entorhino-hippocampal connections.  J Neurosci  19(4):1345-58.  |  Pubmed
 
Alcantara S, Ruiz M, D'Arcangelo G, Ezan F, de Lecea L, Curran T, Sotelo C, Soriano E   (1998)  Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse.  J Neurosci 18(19):7779-99.  | Pubmed
 
Rice DS, Sheldon M, D'Arcangelo G, Nakajima K, Goldowitz D, Curran T (1998)  Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain.  Development  125(18):3719-29.  |  Pubmed
 
Curran T, D'Arcangelo G (1998) Role of reelin in the control of brain development.  Brain Res Brain Res Rev 26(2-3):265-94.  | Pubmed
 
D'Arcangelo G, Curran T (1998) Reeler: new tales on an old mutant mouse.  Bioessays 20(3):235-44.  |  Pubmed
 
Royaux I, Lambert de Rouvroit C, D'Arcangelo G, Demirov D, Goffinet AM (1997) Genomic organization of the mouse reelin gene.  Genomics  46(2):240-50.  |  Pubmed
 
Goldowitz D, Cushing RC, Laywell E, D'Arcangelo G, Sheldon M, Sweet HO, Davisson M, Steindler D, Curran T (1997)  Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of reelin.  J Neurosci  17(22):6767-77.  |  Pubmed
 
Sheldon M, Rice DS, D'Arcangelo G, Yoneshima H, Nakajima K, Mikoshiba K, Howell BW, Cooper JA, Goldowitz D, Curran T (1997)  Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice.  Nature 389(6652):730-3.  |  Pubmed
 
DeSilva U, D'Arcangelo G, Braden W, Chen J, Miao GG, Curran T, Green ED (1997)  The human reelin gene:  isolation, sequencing and mapping on chromosome 7.  Genome Res  7(2):157-64.  |  Pubmed
 
D'Arcangelo G, Nakajima K, Miyata T, Ogawa M, Mikoshiba K, Curran T (1997)  Reelin is secreted glycoprotein recognized by the CR-50 monoclonal antibody.  J Neurosci  17(1):23-31.  |  Pubmed
 
D'Arcangelo G, Habas R, Wang S, Halegoua S, Salton SR (1996)  Activation of codependent transcription factors is required for transcriptional induction of the vgf gene by nerve growth factor and Ras.  Mol Cell Biol 16(9):4861-31.  |  Pubmed
 
D'Arcangelo G, Miao GG, Curran T (1996) Detection of the reelin breakpoint in reeler mice.  Brain Res Mol Brain Res 39(1-2):234-6.  |  Pubmed
 
Curran T, D'Arcangelo G, Goffinet A (1995)  Reeler gene discrepancies  Nat Genet  11(1):12-3.  |  Pubmed
 
D'Arcangelo G, Curran T (1995)  Human genetics.  Smart transcription factors  Nature 376(6538):292-3.  |  Pubmed
 
D'Arcangelo G, Miao GG, Chen SC, Soares HD, Morgan JI, Curran T (1995)  A protein related to extracellular matrix proteins deleted in the mouse mutant reeler.  Nature  374(6524):719-23.  |  Pubmed
 
Salton SR, Volonte C, D'Arcangelo G (1995)  Stimulation of vgf expression by NGF is mediated through multiple signal transduction pathways involving protein phosphorylation.  FEBS Lett  360(2):106-10.  |  Pubmed
 
Miao GG, Smeyne RJ, D'Arcangelo G, Copeland NG, Jenkins NA, Morgan JI, Curran T (1994)  Isolation of an allele of reeler by insertational mutagenesis.  Proc Natl Acad Sci U S A  91(23):11050-4.  |  Pubmed
 
Sharma N, D'Arcangelo G, Kleinlaus A, Halegoua S, Trimmer JS (1993) Nerve growth factor regulates the abundance and distribution of K+ channels in PC12 cells.  J Cell Biol  123(6 Pt 2):1835-43.  |  Pubmed
 
D'Arcangelo G, Paradiso K, Shepherd D, Brehm P, Halegoua S, Mandel G (1993)  Neuronal growth factor regulation of two different sodium channel types through distinct signal transduction pathways.  J Cell Biol 122(4):915-21.  |  Pubmed
 
D'Arcangelo G, Halegoua S (1993) A branched signaling pathway for nerve growth factor is revealed by Src-, Ras-, and Raf-mediated gene inductions.  Mol Cell Biol  13(6):3146-55.  |  Pubmed
 
Wood KW, Qi H, D'Arcangelo G, Armstrong RC, Roberts TM, Halegoua S (1993)  The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction.  Proc Natl Acad Sci U S A  90(11):16-20.  |  Pubmed
 
Thomas SM, DeMarco M, D'Arcangelo G, Halegoua S, Brugge JS  (1992)  Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases.  Cell  68(6):1031-40.  |  Pubmed
 
Kremer NE, D'Arcangelo G, Thomas SM, DeMarco M, Brugge JS, Halegoua S (1991)  Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions.   J Cell Biol  115(3):809-19.  |  Pubmed 
 
Thomas SM, Hayes M, D'Arcangelo G, Armstrong RC, Meyer BE, Zilberstein A, Brugge JS, Halegoua S (1991)  Induction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation.   Mol Cell Biol  11(9):4739-50.  |  Pubmed

 

This site was last updated 10/20/10.