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Publications:
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Jiao, X.,
Chen, H., Chen, J., Herrup, K., Firestein, B.L. and Kiledjian, M.
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Modulation of
Neuritogenesis by a Protein Implicated in X-linked Mental
Retardation. J Neurosci.,
2009, J. Neurosci. 29:12419-12427. |
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[abstract]
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Li, Y., Ho, E.S., Gunderson, S.I. and Kiledjian, M.
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Mutational analysis of a Dcp2 binding element reveals general
enhancement of decapping by 5′
end stem-loop structures. Nucleic Acids Res., 2009, 37:2227-2237
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[abstract]
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Xiang, S., Cooper-Morgan, A., Jiao, X., Kiledjian, M., Manley, J.L., Tong, L.
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Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1. Nature,
2009 458:784-788.
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[abstract]
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Bail, S. and Kiledjian, M.
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Tri-
to be Mono- for Bacterial mRNA Decay.
Structure,
2009 17:317-319.
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[abstract]
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Singh, J., Salcius, M., Liu S.W., Staker, B.L., Mishra, R., Thurmond, J., Michaud, G., Mattoon, D.R., Printen, J., Christensen, J., Bjornsson, J.M., Pollok, B.A., Kiledjian, M., Stewart, L., Jarecki, J. and Gurney, M.E.
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DcpS as a Therapeutic Target for Spinal Muscular Atrophy. ACS Chemical Biology, 2008 3:711-722.
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[abstract]
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Liu, S.W., Welch, S., Jiao, X. and Kiledjian, M.
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Analysis of Mammalian mRNA Decapping. Methods Enzymol.
2008 448:1-21.
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[abstract]
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Bail, S. and Kiledjian, M.
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DcpS, a general modulator of cap-binding protein-dependent processes? RNA Biol. 2008
5:4, 216-219.
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[abstract]
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Lin, M.D., Jiao, X., Grima, D., Newbury, S.F., Kiledjian, M.
and Chou, T.B.
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Drosophila processing bodies in oogenesis. Dev Biol, 2008
322:276-288.
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[abstract]
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Liu, S.W., Rajagopal, V., Patel, S.S.
and Kiledjian, M.
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Mechanistic and kinetic analysis of the DcpS scavenger decapping enzyme. JBC, 2008
283:16427-16436.
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[abstract]
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Shen, V., Liu, H., Liu, S.W., Jiao, X.
and Kiledjian, M.
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DcpS scavenger decapping enzyme can modulate pre-mRNA splicing. RNA, 2008 14:1132-1142.
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[abstract]
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Li, Y., Song, M.G. and Kiledjian, M.
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Transcript-Specific Decapping and Regulated Stability by the human Dcp2 Protein. Mol. Cell. Biol., 2008
28:939-948. |
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[abstract]
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Song, M.G. and Kiledjian, M.
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Terminal Oligo U-tract Mediated Stimulation of Decapping. RNA, 2007
13:2356-2365.
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[abstract] [pdf]
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Bail, S. and Kiledjian, M.
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P-Bodies. McGraw-Hill Yearbook of Science & Technology. McGraw Hill, New York. 2007 171-173.
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Liu, H. and Kiledjian, M.
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An
Erythroid-Enriched Endoribonuclease (ErEN) Involved in a-globin mRNA
Turnover. Protein & Peptide Letters, 2007 14:131-136.
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[abstract]
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Shen, V. and Kiledjian, M.
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A View to a Kill: Structure of the RNA Exosome. Cell, 2006 15:1093-1095.
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[abstract] [pdf]
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Jiao, X., Wang, Z. and Kiledjian, M.
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Identification of an mRNA Decapping Regulator Implicated in X-linked Mental Retardation. Mol. Cell, 2006
24:713-722.
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[abstract] [pdf]
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Liu, H. and Kiledjian, M.
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Decapping the message: a beginning or an end. Biochem Soc Trans., 2006 34:35-38.
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[abstract] [pdf]
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Shen, V. and Kiledjian, M.
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Decapper comes into focus. Structure, 2006 14:171-172.
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[abstract] [pdf]
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Bail, S. and Kiledjian, M.
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More than 1 + 2 in mRNA decapping. Nat Struct Mol Biol., 2006 13:7-9.
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[abstract] [pdf]
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Carr-Schmid, A., Jiao, X. and Kiledjian, M.
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Identification of mRNA bound to RNA binding proteins by differential display. Methods Mol Biol., 2006 317:299-314.
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[abstract]
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Liu, H. and Kiledjian, M.
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Scavenger decapping activity facilitates 5' to 3' mRNA decay. Mol Cell Biol., 2005 25:9764-9772.
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[abstract] [pdf]
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Cohen, L.S., Mihkli, C., Jiao, X., Kiledjian, M., Kunkel, G. and Davis, R.E.
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Dcp2 Decaps m2,2,7GpppN–Capped RNAs and its Activity is Sequence and Context Dependent. Mol Cell Biol., 2005 25: 8779-8791.
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[abstract] [pdf]
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Liu,
S.W., Liu, H., Jiao, X., Gu, M., Lima, C.D., and Kiledjian, M.
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Functional analysis of mRNA scavenger decapping enzymes. RNA, 2004 10:1412-1422.
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[abstract] [pdf]
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Khanna, R. and Kiledjian, M.
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Poly(A)-binding-protein-mediated regulation of hDcp2 decapping in vitro. EMBO J., 2004 23:1968-1976.
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[abstract] [pdf]
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Gu, M.,
Fabrega, C., Liu, S.W., Liu, H., Kiledjian, M., and Lima, C.D.
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Insights into the structure, mechanism and regulation of the scavenger decapping activity. Mol. Cell, 2004 14:67-80.
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[abstract] [pdf]
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Piccirillo, C., Khanna, R. and Kiledjian, M.
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Functional characterization of the mammalian mRNA decapping enzyme hDcp2. RNA, 2003 9:1138-1147.
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[abstract] [pdf]
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Steiger, M., Carr-Schmid, A., Schwartz,, D.C., Kiledjian, M. and Parker, R.
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Analysis of recombinant yeast decapping enzyme. RNA, 2003
9:231-238.
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[abstract] [pdf]
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Rodgers, N.D., Wang, Z., and Kiledjian, M.
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Regulated a-globin mRNA decay is a cytoplasmic event proceeding through 3'-to-5' exosome-dependent decapping. RNA, 2002
12:1526-1537.
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[abstract] [pdf]
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Wang, Z., Jiao, X., Carr-Schmid, A. and Kiledjian, M.
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The hDcp2 protein is a mammalian mRNA decapping enzyme. Proc Natl Acad Sci U S A., 2002 99:12663-12668.
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[abstract] [pdf]
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Liu, H., Rodgers, N., Jiao, X, and Kiledjian, M.
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The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases. EMBO J., 2002 21:4699-4708.
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[abstract] [pdf]
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Rodgers, N.D.., Jiao, X, and Kiledjian, M.
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Identifying mRNAs bound by RNA-binding proteins using affinity purification and differential display. Methods, 2002 26:115-122.
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[abstract] [pdf]
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Jiao, X., Trifillis, P. and Kiledjian, M.
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Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein. Biol Reprod., 2002 66:475-485.
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[abstract] [pdf]
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Rodgers, N., Wang, Z, and Kiledjian, M.
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Characterization and purification of a mammalian endoribonuclease specific for the alpha -globin mRNA. J Biol Chem., 2002 277:2597-2604.
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[abstract] [pdf]
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Wang, Z, and Kiledjian, M.
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Functional link between the mammalian exosome and mRNA decapping. Cell, 2001 107:751-762.
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[abstract] [pdf]
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Wang, Z. and Kiledjian, M.
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The poly(A)-binding protein and an mRNA stability protein jointly regulate an endoribonuclease activity. Mol Cell Biol., 2000 20:6334-6341.
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[abstract] [pdf]
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Wang, Z. and Kiledjian, M.
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Identification of an erythroid-enriched endoribonuclease activity involved in specific mRNA cleavage. EMBO J., 2000 22:295-305.
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[abstract] [pdf]
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Barnhart, B., .Kosinski, P., Wang, Z., Ford, G.S., Kiledjian, M. and Covey, L.R.
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Identification of a Complex that binds to the CD154 3´UTR: Implications for a Role in Message Stability during T cell Activation. J. Immunology, 2000 165:4478-4486
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[abstract] [pdf]
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Trifillis, P., Day, N. and Kiledjian, M.
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Finding the right RNA: identification of cellular mRNA substrates for RNA-binding proteins. RNA, 1999 5:1071-1082
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[abstract] [pdf]
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Wang, Z, Day, N., Trifillis, P. and Kiledjian, M.
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An mRNA stability complex functions with poly(A)-binding protein to stabilize mRNA in vitro. Mol Cell Biol., 1999 19:4552-4560
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[abstract] [pdf]
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Kiledjian, M., Day, N., and Trifillis, P.
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Purification and RNA-binding properties of the Polycytidylate-Binding Proteins aCP1 and aCP2. Methods, 1999 17:84-91
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[abstract] [pdf]
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Kiledjian, M., DeMaria, C.T., Brewer, G. and Novick, K.
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Identification of AUF1 (heterogeneous nuclear ribonucleoprotein D) as a component of the alpha-globin mRNA stability complex. Mol Cell Biol, 1997 17:4870-4876
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[abstract] [pdf]
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