MOLECULAR BIOLOGY (146:478)

S'2010

                       

Note:  Unless indicated otherwise, all assigned chapters are in reference to the textbook "Molecular Biology" 4th Edition (2008)  by Robert Weaver (MCB/McGraw Hill)

 

 

Schedule of classes

 

DATE                    TOPIC                                                                                      ASSIGNMENT

 

Jan 20                    DNA structure and function, ppt, pdf                                          Chapters 1 & 2

Jan 23                    DNA as the primary genetic material, ppt, pdf                             Chapter 1 & 2

Jan 27                    Protein structure and function - I, ppt, pdf                                   Chapter 3 & others

Jan 30                    Protein structure and function - II, ppt, pdf                                  Chapter 3 & others

Feb 3                     Conference I,   pdf                                                                   Assigned materials

                              Problem set I due,   pdf

Feb 6                     Recombinant DNA techniques - I, ppt, pdf                                 Chapter 4

Feb 10                   Recombinant DNA techniques - II, ppt, pdf                                Chap 5 & assigned 

Feb 13                   Biophysical methods for studying macromolecules1                      Assigned materials

                              ppt, pdf

Feb 17 & 20          Analytical methods for studying proteins, ppt, pdf                        Chap 5 & assigned

Feb 24                   Conference II, pdf                                                                   Assigned materials

                              Problem set II  due ,   pdf

Feb 27 (Fri)           Hourly exam I

March 3                 DNA replication, ppt, pdf                                                           Chapter 20

March 6                 Prokaryotic transcription, ppt, pdf                                              Chapter 6

March 10               Regulation of gene expression in prokaryotes - I, ppt, pdf           Chapter 7

March 13               Regulation of gene expression in prokaryotes - II, ppt, pdf          Chapter 7 & 8

March 17 &20      Spring recess

March 24 &27       Eukaryotic transcription and transcription factors, ppt, pdf           Chap 10, 11 (transcrip)

                                                                                                                                Chap 9 &12 (TF)

March 31               Chromatin structure and eukaryotic transcription, ppt, pdf           Chapter 13

April 3                    Recombinant DNA and genetic diseases, ppt, pdf                       Assigned materials

                              Problem set III  due,   pdf

April 7 (Tue)         Hourly Exam II

 

April 10                 Post-transcriptional control: Splicing & polyadenylation2              Watson 13

April 14                 Post transcriptional events - Splicing & polyadenylation2             Watson 13

April 17                 Post transcriptional events - Splicing & polyadenylation2             Watson 13

April 21                 RNA world, Ribozymes, RNA splicing 2                                     Watson 13

April 24                 Control of mRNA translation, stability, localization 2                    Watson 14

April 28                 Translation: Bacterial and eukaryotic2                                          Watson 14, 15 

May 1                    Course review & Conference III,   pdf                                     Assigned materials

                              Problem set IV is due ,   pdf

 

 

May 7                  Final Examination,  12:00 – 3:00 pm, ARC 105

(Wednesday)         

 

 

 

Guest lecturers:

1Dr. K.Y. Chen; 2Dr. Sam Gunderson

 

If you are interested in viewing the slide presentation of my lectures, please contact me (732-445-2730; liu@biology.rutgers.edu) and I shall provide you with a userID/password for the course website.