Jody Hey Professor Rutgers University Department of Genetics Nelson Biological Laboratories Room B326A Piscataway. NJ 08854 (732) 445-5272 FAX - 5870 hey@biology.rutgers.edu Visit Dr. Hey's Lab!

Evolution. speciation. human origins. recombination. natural selection. codon bias

I conduct basic research in the area of evolutionary genetics. with a general goal of better understanding the mechanisms of evolution. Specific research areas include the origins of biological species. the evolution of recombination. and the origins of modern humans. My research methods are roughly split between empirical molecular biological methods and the mathematical and statistical modelling of evolutionary processes.

Selected Publications

Hey J. (2007) A model in two acts: a commentary on 'A model detectable alleles in a finite population' by Timoko Ohta and Motoo Kimura. Genet Res. 89(5-6):365-6.

Hoelzel AR, Hey J, Dahlheim ME, Nicholson C, Burkanov V, Black N. (2007) Evolution of population structure in a highly social top predator, the killer whale. Mol Biol Evol. 24(6):1407-15.

Hey, J. and Nielsen, R. (2007). Integration within the Felsenstein equation for improved Markov chain Monte Carlo methods in population genetics. PNAS 104:2785–2790.

Shimada, M. K., Panchapakesan, K., Tishkoff, S. A., Nato, Jr, A. Q. and Hey, J. (2007). Divergent haplotypes and human history as revealed in a worldwide survey of X-Linked DNA sequence variation. Mol Biol Evol 24:687-698.

Hey J. (2006). Recent advances in assessing gene flow between diverging populations and species. Current Opinion in Genetics & Development 16:592-596.

Hey J. On the failure of modern species concepts. Trends Ecol Evol. (2006) Trends Ecol Evol 21:447-450.

Won YJ. Wang Y. Sivasundar A. Raincrow J. Hey J. (2006) Nuclear gene variation and molecular dating of the cichlid species flock of Lake Malawi. Mol Biol Evol. 23(4):828-37.

Sivasundar A. Hey J. (2005) Sampling from natural populations with RNAI reveals high outcrossing and population structure in Caenorhabditis elegans. Curr Biol. 15(17):1598-602.

Hey J. (2005) On the number of New World founders: a population genetic portrait of the peopling of the Americas. PLoS Biol. 3(6):e193.

Won. Y. J.. Sivasundar. A.. Wang. Y. and Hey. J. (2005). On the origin of Lake Malawi cichlids: a population genetic analysis of divergence. Proc Natl Acad Sci U S A (in press).

Won. Y. J.. and Hey. J. (2005). Divergence population genetics of chimpanzees. Mol Biol Evol 22:297-307.

Hey. J.. and Nielsen. R. (2004). Multilocus methods for estimating population sizes. migration rates and divergence time. with applications to the divergence of Drosophila pseudoobscura and D. persimilis. Genetics 167:747-760.

Hey. J.. Won. Y.-J.. Sivasundar. A.. Nielsen. R. and Markert. J. A. (2004) Using nuclear haplotypes with microsatellites to study gene flow between recently separated populations. Molecular Ecology in press

Hey J.. Waples R.S.. Arnold M.L.. Butlin R.K. & Harrison R.G. (2003) Understanding and confronting species uncertainty in biology and conservation. Trends in Ecology and Evolution 18:597-603.

Hey. J.. and Machado. C. A. (2003). The study of structured populations--new hope for a difficult and divided science. Nat Rev Genet 4:535-43.

Machado. C. A.. and Hey. J. (2003). The causes of phylogenetic conflict in a classic Drosophila species group. Proceedings of the Royal Society. London. Series B 270:1193-1202.

Sivasundar. A.. and Hey. J. (2003). Population Genetics of Caenorhabditis elegans. The paradox of low polymorphism in a widespread species. Genetics 163:147-57.

Ortíz-Barrientos. D.. Reiland. J.. Hey. J. and Noor. M. (2002). Recombination and divergence of hybridizing species. Genetica 115:167-178.

Machado. C.. Kliman. JR. M.. Markert. M. and Hey. J. (2002) Inferring the history of speciation from multilocus DNA sequence data: the case of Drosophila pseudoobscura and its close relatives. Mol. Biol. Evol. 19: 472-488.

Hey. J.. and Kliman. R. M. (2002) Interactions between natural selection. recombination and gene density in the genes of Drosophila. Genetics 160: 595-608.

Hey. J. ((2001)) Genes. Categories. and Species: the evolutionary and cognitive causes of the species problem. Oxford University Press. NY.

Hey. J. (2001) The mind of the species problem. Trends in Ecology and Evolution 16: 326-329.

Harris. E. E. and Hey. J. (2001) Human populations show reduced DNA sequence variation at the Factor IX locus. Current Biology 11: 774-778.

Kliman. R. M.. Andolfatto. P.. Coyne. J. A.. Depaulis. F.. Kreitman. M.. Berry. A. J.. McCarter. J.. Wakeley. J. and Hey. J. (2000) The population genetics of the origin and divergence of the Drosophila simulans complex species. Genetics 156:1913-1931.