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Chung S. Yang
Professor
Rutgers University
Department of Chemical Biology
Ernest Mario School of Pharmacy
164 Frelinghuysen Road
Piscataway. N.J. 08854-0789
(732) 445-3400. Ext 248
FAX -0687
csyang@rci.rutgers.edu |
Molecular mechanisms of carcinogenesis and its prevention
The research program is focused
on studying the molecular mechanisms of carcinogenesis and designing
strategies and agents for the prevention of cancer. Specific projects
involve: 1) characterizing the molecular alterations at different stages
of esophageal cancer development in animal models and human tissues; 2)
studying inflammation. carcinogenesis. and cancer prevention in animal
models for esophageal adenocarcinoma and ulcerative colitis-associated
colon carcinogenesis; 3) studying the cancer preventive activity of tea. curcumin. genistein. and other dietary constituents. and combinations
thereof with synthetic compounds in animal models for lung. oral. esophageal. intestinal. and colon cancers. The molecular mechanisms of
action as well as the metabolism and bioavailability of these compounds
are being studied in cell lines. animal models. and humans.
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